Mucosa-like differentiation of head and neck cancer cells is inducible and drives the epigenetic loss of cell malignancy

Abstract Head and neck squamous cell carcinoma (HNSCC) is a highly malignant disease with high death rates that have remained substantially unaltered for decades.Therefore, new treatment approaches are urgently needed.Human papillomavirus-negative tumors harbor areas of Mystery Minis terminally differentiated tissue that are characterized by cornif

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GlPRMT5 inhibits GlPP2C1 via symmetric dimethylation and regulates the biosynthesis of secondary metabolites in Ganoderma lucidum

Abstract PRMT5, Diamond Select a type II arginine methyltransferase, is involved in transcriptional regulation, RNA processing and other biological processes and signal transduction.Secondary metabolites are vital pharmacological compounds in Ganoderma lucidum, and their content is an important indicator for evaluating the quality of G.lucidum.Here

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